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Research about Biologic Therapies Options
Paula-C
#1 Posted : Monday, June 11, 2012 6:40:26 PM Quote
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Been thinking about posting this since yesterday, been in two minds really. Just a little worried that someone just diagnosed with RA and starting their journey might be a bit alarmed. But on the other hand someone being offered anti tnf's and a little worried about it all, after reading this may well decided to take them. It's made my view on anti tnf's change.

t's from Arthritis Research UK's web page:

http://www.arthritisrese...arthritis-patients.aspx

There is also some interesting reading on NRAS homepage

http://www.nras.org.uk/c...uropean_neighbours.aspx

Paula x

Naomi1
#2 Posted : Tuesday, June 12, 2012 12:15:24 AM Quote
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Thanks Paula. interesting reading. Best wishes from Naomi.
Merielpb
#3 Posted : Tuesday, June 12, 2012 10:07:22 AM Quote
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I had my 1st assessment for anti-TNF on Friday & I was a bit ambivalent but now I hope I do qualify
Rebecca D
#4 Posted : Tuesday, June 12, 2012 12:18:29 PM Quote
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Thanks for posting this Paula, I think it will help alot of people, especially the newly diagnosed.

In my opinion anti-tnfs are far more superior drugs than other DMARDS at suppressing the disease. But the downside to anti-tnfs, is the risk of serious infection is much greater and this is something everyone has to weigh up before going on anti-tnf. In the past 12 months I have had a continuous round of serious lung infections, all due to taking Enbrel but on the up side Enbrel-anti-tnf is the only drug I can tolerate and the only drug that lowers my inflammation.

Love
Rebecca x
smith-j
#5 Posted : Tuesday, June 12, 2012 8:09:28 PM Quote
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Thanks for posting this Paula.

I am on my third anti-tnf, Simponi, and think I have finally found "the one". In all the time I have been taking Methotrexate and trying all the other anti-tnf's, I have never had an infection (fingers crossed as she says it), so it does not always follow that something dire is going to happen when you take them.

Jackie
xx
jenni_b
#6 Posted : Wednesday, June 13, 2012 10:00:16 AM Quote
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I think these articles are ever so important.
As with all things it's about 'balancing risk to benefit ratios' according to my rheummy team.

This is not English,

The translation is 'you're really sick and we have to do something so we are giving you this stuff and keeping our fingers crossed!'

There is no doubt that the biologics have changed the ra treatments beyond recognition in the last 15 yrs or so.
So many people I meet are doing brilliantly on them and almost in remission

Some seem to have them for years with no troubles infection wise etc at all and then there area few people with a few issues then there are the real pain in the bum ones like me that give rheumatologists nightmares!

I'm pleased about the articles though because there are some stubborn old fashioned drs you meet with little experience of the illness who, when you present with persistent urine infections/ nasty cough on these drugs still want to fob you off and give you no anti bioticsScared When they MUST treat you and FAST.

these reports will help us in that way.
And if we don't get the dr to listen we can always bat them about the head with the rptsBigGrin
how to be a velvet bulldoser
jeanb
#7 Posted : Wednesday, June 13, 2012 11:53:42 AM Quote
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Watching all this with interest as soon to go on anti-tnf. Having finally given in and decided I just can't cope anymore on mtx and hydroxychloroquine (ESR 174, CRP 105, ALT 132 etc etc etc yawn yawn boring boring). I've resisted this for SOOOOOOOO long but according to recent X-rays and scans things are deteriorating at a rate of knots. Even the joints that don't hurt are crumbling away!!! I've also got Vascular Calcification in my right (replaced) knee and can't seem to find out what the heck it is. Any ideas??

Sorry I haven't been around much lately but been too bad most of the time to get out of bed.

Love to all
Jean
suzanne_p
#8 Posted : Wednesday, June 13, 2012 12:14:29 PM Quote
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thanks for the info Paula,

i know i tend to bury my head in the sand when i'm faced with a new drug .. and i did this very well when i started Humira last August, i did watch the DVD and listen to my Nurse but i just felt i couldn't thoroughly read any literature. i prefer to chat about it so also rang NRAS Helpline.

now i'm established on it it's good to read the info in the article, we all deserve to be as comfortable as possible with with awful RA, and i am sure this will give support to those about to start on one.

sorry to hear you're having a rough time Jean x

Suzanne x



jeanb
#9 Posted : Wednesday, June 13, 2012 1:35:09 PM Quote
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Thanks Suzanne - but I'm a bit like Arny - I'll be back!!!!
Paula-C
#10 Posted : Wednesday, June 13, 2012 3:13:59 PM Quote
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I was worried a little when I put the post up. Worried that I may of made people newly diagnosed worried about heart problems and the article mentioning the D word. Nobody would think that people can die as a result of arthritis would they?

Got some good replies from you all so I am glad that I did, especially from people who may or are facing making the decision about taking it.

Jean...........So sorry to hear about things, been thinking about you not posting on here much, can understand why now. You were still your lovely bubbly self when I saw you at Coventry.....sending a big ((((((HUG)))))) and hope things improve for you soon.

I have also seen an interesting article about RoActemra

http://www.ibtimes.co.uk...arthritis-patients.html

Paula x
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